[Joint CQSE & NCTS Seminar] Fluorescent Nanodiamond with Nitrogen-Vacancy Centers: A Biocompatible Quantum Material
Title: [Joint CQSE & NCTS Seminar] Fluorescent Nanodiamond with Nitrogen-Vacancy Centers: A Biocompatible Quantum Material
Speaker: Dr. Huan-Cheng Chang (Academia Sinica)
Time: 2025/09/05 (Fri.) 14:20-16:20
Place: Rm. 104, Chin-Pao Yang Lecture Hall, Department of Physics/CCMS, NTU
Online: https://nationaltaiwanuniversity-zbh.my.webex.com/nationaltaiwanuniversity-zbh.my/j.php?MTID=m35c57ceb3c91fd5af3ca30d927e989a1
Abstract
Nitrogen-vacancy (NV) centers in diamond are among the most versatile solid-state quantum systems, uniquely combining stable optical emission with coherent electronic spin states that can be initialized, manipulated, and read out at room temperature. Remarkably, they can be readily detected at the single NV level, enabling quantum measurements with nanometer-scale precision. When incorporated into fluorescent nanodiamonds (FNDs), NV centers retain the intrinsic biocompatibility and chemical robustness of diamond, yielding a quantum material ideally suited for both biomedical and technological applications. This lecture will highlight the quantum properties of NV centers, such as spin-dependent fluorescence, long spin coherence times, and nanoscale sensitivity to magnetic, electric, and thermal environments, and their use in high-resolution bioimaging as well as quantum sensing applications in semiconductor devices. Methods for controlled implantation of NV centers in bulk diamonds and scalable production of NV-rich nanodiamonds will also be presented. By bridging the fundamental physics of NV centers with the practicality of nanodiamond carriers, FNDs emerge as a powerful platform at the intersection of quantum technologies, biomedicine, and semiconductor engineering.Biography
Huan-Cheng Chang is a Distinguished Research Fellow at the Institute of Atomic and Molecular Sciences (IAMS), Academia Sinica. His research lies at the intersection of physical chemistry, nanoscience, and biomedical engineering. In 2005, he pioneered the development of fluorescent nanodiamonds (FNDs) containing nitrogen-vacancy (NV) spin defects and demonstrated their use in cellular imaging, marking a significant advancement in the field of nanotechnology. He further contributed to the field by developing a method for the mass production of FNDs in 2008, bridging the gap between fundamental research and practical biomedical applications. His innovations culminated in a U.S. patent for “Luminescent Diamond Particles” in 2012. Beyond his technical contributions, Dr. Chang has authored over 180 peer-reviewed publications related to nanodiamonds, including the comprehensive monograph titled Fluorescent Nanodiamonds in 2019. His current research focuses on advancing FND-based technologies and exploring their quantum sensing applications in biomedical and semiconductor systems.
